21266a
Lecture
SoSe 18: Polymeric and macromolecular therapeutic and diagnostic agents
Marcelo Calderón
Comments
Program:
- Basics on drug classes (modes of action, chemical examples)
- Background on biology and pharmacology (absorption, distribution, metabolism, excretion, toxicity)
- Principles of drug delivery with polymers (drug transport, drug release)
- Chemistry on polymers and macroarchitectures
- Synthesis of bioconjugates (conjugation chemistry, linkers, reactive groups)
- Multivalency /Polyvalency as novel mode of action
- Functional dendritic polymers for biomedical applications
- Nanocomposites
- Basics on pharmaceutical drug development
- Discussion of examples from literature and market
The exam will consist in a talk / ppt presentation about a recent publication (10-15 min) related to at least one of the topics studied during the course followed by 10-15 min questions, half on the topic of the publication, half on the lecture in general.
Moreover the students will be asked to discuss papers once during the lecture as training for the exam.
Jr.-Prof. Dr. Marcelo Calderon Institut für Chemie und Biochemie Marcelo Calderon, marcelo.calderon@fu-berlin.de http://www.bcp.fu-berlin.de/en/chemie/oc/calderon/index.html close
Suggested reading
1. Polymer Therapeutics I: Polymers as Drugs, Conjugates and Gene Delivery Systems. Edited by R. Satchi-Fainaro and R. Duncan. Springer, Berlin-Heidelberg-New York, 2006, ISBN: 978-3-540-29210-4.
2. Polymer Therapeutics II: Polymers as Drugs, Conjugates and Gene Delivery Systems. Edited by R. Satchi-Fainaro and R. Duncan. Springer, Berlin-Heidelberg-New York, 2006, ISBN: 978-3-540-29211-1.
3. Chemistry of Bioconjugates: Synthesis, Characterization, and Biomedical Applications. Edited by Ravin Narain. John Wiley & Sons, New Jersey, 2014, ISBN: 978-1-118-35914-3.
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13 Class schedule
Additional appointments
Thu, 2018-07-26 14:00 - 18:00Exam/Final Oral Presentation: 21266a/b - Polymeric and Macromolecular Therapeutic and Diagnostic Agents
Thu, 2018-08-02 14:00 - 18:00
Exam/Final Oral Presentation: 21266a/b - Polymeric and Macromolecular Therapeutic and Diagnostic Agents
Regular appointments
Thu, 2018-04-19 14:00 - 16:00
Thu, 2018-04-26 14:00 - 16:00
Thu, 2018-05-03 14:00 - 16:00
Thu, 2018-05-17 14:00 - 16:00
Thu, 2018-05-24 14:00 - 16:00
Thu, 2018-05-31 14:00 - 16:00
Thu, 2018-06-07 14:00 - 16:00
Thu, 2018-06-14 14:00 - 16:00
Thu, 2018-06-21 14:00 - 16:00
Thu, 2018-06-28 14:00 - 16:00
Thu, 2018-07-05 14:00 - 16:00
Thu, 2018-07-12 14:00 - 16:00
Thu, 2018-07-19 14:00 - 16:00