21266a

SoSe 18: Polymeric and macromolecular therapeutic and diagnostic agents

Marcelo Calderón

Kommentar

Program: - Basics on drug classes (modes of action, chemical examples) - Background on biology and pharmacology (absorption, distribution, metabolism, excretion, toxicity) - Principles of drug delivery with polymers (drug transport, drug release) - Chemistry on polymers and macroarchitectures - Synthesis of bioconjugates (conjugation chemistry, linkers, reactive groups) - Multivalency /Polyvalency as novel mode of action - Functional dendritic polymers for biomedical applications - Nanocomposites - Basics on pharmaceutical drug development - Discussion of examples from literature and market The exam will consist in a talk / ppt presentation about a recent publication (10-15 min) related to at least one of the topics studied during the course followed by 10-15 min questions, half on the topic of the publication, half on the lecture in general. Moreover the students will be asked to discuss papers once during the lecture as training for the exam. Jr.-Prof. Dr. Marcelo Calderon Institut für Chemie und Biochemie Marcelo Calderon, marcelo.calderon@fu-berlin.de http://www.bcp.fu-berlin.de/en/chemie/oc/calderon/index.html Schließen

Literaturhinweise

1. Polymer Therapeutics I: Polymers as Drugs, Conjugates and Gene Delivery Systems. Edited by R. Satchi-Fainaro and R. Duncan. Springer, Berlin-Heidelberg-New York, 2006, ISBN: 978-3-540-29210-4. 2. Polymer Therapeutics II: Polymers as Drugs, Conjugates and Gene Delivery Systems. Edited by R. Satchi-Fainaro and R. Duncan. Springer, Berlin-Heidelberg-New York, 2006, ISBN: 978-3-540-29211-1. 3. Chemistry of Bioconjugates: Synthesis, Characterization, and Biomedical Applications. Edited by Ravin Narain. John Wiley & Sons, New Jersey, 2014, ISBN: 978-1-118-35914-3. Schließen

13 Termine

Zusätzliche Termine

Do, 26.07.2018 14:00 - 18:00

Exam/Final Oral Presentation: 21266a/b - Polymeric and Macromolecular Therapeutic and Diagnostic Agents

Dozenten:
Prof. Dr. Marcelo Calderón