21266a
Lecture
WiSe 16/17: Polymeric and macromolecular therapeutic and diagnostic agents
Marcelo Calderón
Comments
Outline
• Basics on drug classes for therapy and diagnostic imaging.
• Basics on pathophysiology: genetic diseases, human viral diseases, cancer.
• Background on pharmacology, active and passive targeting in cancer therapy.
• Classes of polymer therapeutics: polymeric drug or sequestrant, polymer-drug conjugates, polymer-protein conjugates.
• Multivalent macromolecular architectures: dendrimers, hyperbranched polymers, dendronized polymers. Multivalency as novel mode of action.
• Polymer based therapeutics such as gels (nanogels, hydrogels), nanospheres, microspheres.
• Polymers and macromolecules for gene therapy (concept of polyelectrolyte): dendriplexes, polyplexes. • Nanotheranostics, biological fate of polymeric particles.
• Clinical approval of polymer therapeutics.
Jun.-Prof. Dr. Marcelo Calderon
Institut für Chemie und Biochemie
marcelo.calderon@fu-berlin.de
http://www.bcp.fu-berlin.de/chemie/calderon close
• Basics on drug classes for therapy and diagnostic imaging.
• Basics on pathophysiology: genetic diseases, human viral diseases, cancer.
• Background on pharmacology, active and passive targeting in cancer therapy.
• Classes of polymer therapeutics: polymeric drug or sequestrant, polymer-drug conjugates, polymer-protein conjugates.
• Multivalent macromolecular architectures: dendrimers, hyperbranched polymers, dendronized polymers. Multivalency as novel mode of action.
• Polymer based therapeutics such as gels (nanogels, hydrogels), nanospheres, microspheres.
• Polymers and macromolecules for gene therapy (concept of polyelectrolyte): dendriplexes, polyplexes. • Nanotheranostics, biological fate of polymeric particles.
• Clinical approval of polymer therapeutics.
Jun.-Prof. Dr. Marcelo Calderon
Institut für Chemie und Biochemie
marcelo.calderon@fu-berlin.de
http://www.bcp.fu-berlin.de/chemie/calderon close
16 Class schedule
Regular appointments
Thu, 2016-10-20 14:00 - 16:00
Thu, 2016-10-27 14:00 - 16:00
Thu, 2016-11-03 14:00 - 16:00
Thu, 2016-11-10 14:00 - 16:00
Thu, 2016-11-17 14:00 - 16:00
Thu, 2016-11-24 14:00 - 16:00
Thu, 2016-12-01 14:00 - 16:00
Thu, 2016-12-08 14:00 - 16:00
Thu, 2016-12-15 14:00 - 16:00
Thu, 2017-01-05 14:00 - 16:00
Thu, 2017-01-12 14:00 - 16:00
Thu, 2017-01-19 14:00 - 16:00
Thu, 2017-01-26 14:00 - 16:00
Thu, 2017-02-02 14:00 - 16:00
Thu, 2017-02-09 14:00 - 16:00
Thu, 2017-02-16 14:00 - 16:00