Björn Fischer-Zirnsak, Daniel Murad Ibrahim, Uwe Kornak, Martin Atte Mensah, Dominik Seelow
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Foundations in Bio-Medicine
This series of seminars and tutorials gives an introduction into how information is stored in the genome, how this information replicated and passed on ... read more
Foundations in Bio-Medicine
This series of seminars and tutorials gives an introduction into how information is stored in the genome, how this information replicated and passed on to daughter cells and within the germline, and how it is read out to give rise to the living organism. The origin and consequences of germline and somatic genomic variability on the cellular and phenotypic level will be discussed as well as the methods for genome analysis including aspects of data processing and safety. Using different human hereditary disorders as examples pathological changes in cellular compartments and in the 3D structure of the genome and the consequences on gene regulation will be explained. The aim is a broad overview over the use of genomic data in clinical medicine.