216101a

WiSe 22/23: Advanced Biochemistry - Part 1: Nucleic Acids and Proteins

Sutapa Chakrabarti, Christian Freund, Florian Heyd, Alexander Meissner, Markus Wahl, Tugçe Aktas-Ilik, Fan Liu, Sebastian Rämisch

Information for students

For the completion of the module the attendance of both parts of the lecture (216101a and c) as well as both seminars (216101b and d) is needed. Further information about blackboard.

Comments

Qualifikationsziele: Die Studentinnen und Studenten beitzen ein aktuelles und strukturiertes Fachwissen in den Forschungsfeldern der Strukturbiochemie, der Molekularbiologie und der molekularen Biomedizin. Sie können Forschungsrichtungen einschätzen und ihre zukünftige Spezialisierungsrichtung bestimmen.

Inhalte: Aktuelle Entwicklungen der Forschungsfelder Strukturbiochemie, molekulare Zellbiologie und molekulare Medizin.
U.A.:

Co-transcriptional pre-mRNA processing
RNA degradation and quality control
Pre-mRNA splicing
RNA transport and localization
RNA remodeling by helicases
Small and long non-coding RNAs
Protein folding
Protein production in cell-free systems
Protein engineering
Dynamic aspects of protein structure
The role of protein folding in ageing and neuro-degenerative disease
Modeling of protein dynamics
Protein folding in vitro
--> Hydrogen/deuterium exchange
--> Fluorescence based methods
--> Folding at the ribosome
Protein folding and dynamics as described in silico and experimentally by NMR
Protein expression
Protein folding inside the cell
--> Chaperone-assisted folding
--> Folding in the ER
--> Protein misfolding disease

Dr. T. Aktas: aktas@molgen.mpg.de
Prof. Dr. S. Chakrabarti: chakraba@zedat.fu-berlin.de
Prof. Dr. C. Freund: chfreund@zedat.fu-berlin.de
Prof. Dr. F. Heyd: florian.heyd@fu-berlin.de
Prof. Dr. M. Wahl: mwahl@zedat.fu-berlin.de
Prof. Dr. A. Meissner: office-meissner@molgen.mpg.de close

14 Class schedule

Additional appointments

Fri, 2023-02-10 15:00 - 16:30

Klausur 216101 a

Lecturers:
Univ.-Prof. Sutapa Chakrabarti
Dr. Tugçe Aktas-Ilik
Univ.-Prof. Dr. Christian Freund
Univ.-Prof. Dr. Florian Heyd
Prof. Dr. Alexander Meissner
Prof. Dr. Fan Liu
Dr.rer.nat. Sebastian Rämisch
Univ.-Prof. Markus Wahl