Joint class taught by the Institute of Clinical Physiology and the Institute of Physiology at the Charité.

Contents:

Using selected, up-to-date examples from biology and physiology, the work steps from data acquisition, data processing, data preparation, data assessment to the modeling of complex physiological relationships are studied theoretically and practically. Models from the following areas are dealt with in more detail:

- Basic biophysical and biochemical processes (e.g. free and facilitated diffusion through channel and transport proteins, active ion transport through membrane transporters, receptor-ligand interaction, interaction of structural and motor proteins)

- Structure-function analysis of transport proteins

- Biological networks (e.g. signal networks, metabolic networks, transportome models, feedback-mechanisms)

- Modeling physiological functions of an organism (e.g. mass transfer to the kidney, blood- and immune-function, muscle movement, temperature regulation, circadian rhythm, cardiac- and circulatory function, autonomic regulation / heart-rate-variability, body-composition)

The course will be split into two segments: the first seven appointments in the semester will take place at the Institute of Physiology, while the second seven appointments will take place at the Institute of Clinical Physiology.